As the sun sets and the day’s hustle eases, I find myself craving a warm, comforting meal that wraps me in nostalgia. Enter my Easy Homemade Ground Beef Casserole, a one-dish wonder that marries tender penne pasta with flavorful ground beef, rich marinara, and gooey cheddar cheese. Not only is this dish quick to prepare, but it’s also the type of comfort food that whispers “home” with each forkful. Perfect for those busy weeknights, it’s a family-friendly dinner that satisfies even the pickiest eaters. Plus, it’s make-ahead friendly, meaning you can enjoy your evening with loved ones instead of being stuck in the kitchen. Are you ready to create a cozy masterpiece that’ll keep everyone coming back for seconds?

Why is this Ground Beef Casserole a Must-Try?

Convenience: This casserole is a weeknight lifesaver, requiring minimal prep and just one dish for cooking!

Crowd-pleaser: Its rich flavors and cheesy goodness will make it a hit with family and friends, even the picky eaters!

Flexible: Customize it easily—try using ground turkey for a healthier twist or swap in your favorite cheese to mix things up.

Make-Ahead Magic: You can prepare it in advance, letting you enjoy more quality time with loved ones and a stress-free dinner.

Ultimate Comfort: With every bite of cheesy, savory goodness, this dish truly embodies comfort, transporting you back to heartwarming dinners at home.

If you’re looking for more comforting meals, check out my easy recipe for Ground Beef Cabbage or a flavorful Ranch Beef Bowtie.

Homemade Ground Beef Casserole Ingredients

For the Casserole

Penne Pasta – Provides the structure of the casserole; cook al dente to prevent it from getting mushy.
Olive Oil – Adds moisture and flavor; can be substituted with canola or vegetable oil if desired.
Ground Beef (1 lb) – The main protein source; use 85/15 for perfect flavor and moisture, or leaner cuts (90/10) but add extra oil.
Onion (1 medium, finely diced) – Enhances overall flavor; sauté until softened for the best results.
Garlic (2 cloves, minced) – Adds aromatic depth; incorporate it towards the end of cooking the beef for maximum flavors.
Marinara Sauce (2 cups) – Brings the dish together with a burst of flavor and moisture; if you’re looking for quality, Rao’s is a top choice.
Salt & Black Pepper – Essential seasonings; adjust to your personal taste for the perfect balance.
Cheddar Cheese (2 cups, shredded) – Provides that melty, creamy topping; mozzarella can easily substitute for a lighter flavor.

Optional Topping

Fresh Basil or Parsley – Adds a fresh flavor and vibrant color to your dish; sprinkle on top before serving for that extra touch.

Step‑by‑Step Instructions for Homemade Ground Beef Casserole

Step 1: Preheat and Prepare
Begin by preheating your oven to 400°F (200°C). While it warms up, grease a 9×13 inch baking dish with olive oil or non-stick spray to ensure easy serving later. The right dish size is crucial for the perfect bake, so make sure it’s ready to hold all the delicious layers of this Homemade Ground Beef Casserole.

Step 2: Cook the Pasta
Bring a large pot of salted water to a rolling boil, then add the penne pasta. Cook for 7 to 8 minutes, allowing the pasta to remain al dente. Drain the cooked pasta and set it aside in a colander to prevent additional cooking. This texture will help maintain the integrity of the casserole when baked.

Step 3: Sauté the Aromatics and Beef
In a large skillet, heat a drizzle of olive oil over medium-high heat. Add the finely diced onion and ground beef, cooking for about 10 minutes. Stir occasionally, ensuring the beef is browned thoroughly and the onions are softened. You want the beef to take on a rich color, signaling it’s ready to blend with the marinara.

Step 4: Add Garlic and Season
Once the beef is browned, stir in the minced garlic and cook for an additional 30 seconds until fragrant. This quick step enhances the flavor profile of your Homemade Ground Beef Casserole. Next, season the mixture with salt and pepper to taste, enjoying the growing aroma as it mingles with the sautéed ingredients.

Step 5: Incorporate the Marinara Sauce
Pour in the marinara sauce, stirring well to combine with the beef and vegetables. Allow the mixture to simmer for 1-2 minutes, creating a cohesive filling for your casserole. This will soften the flavors and add moisture, ensuring every bite of the casserole remains juicy and delightful.

Step 6: Combine and Transfer
Gently fold the drained penne pasta into the beef and marinara mixture, ensuring every piece of pasta is coated. Carefully transfer this hearty mixture into the greased baking dish, spreading it evenly. This step is essential for even cooking and ensures that each serving of your Homemade Ground Beef Casserole is packed full of flavor.

Step 7: Top with Cheese
Sprinkle the shredded cheddar cheese generously over the pasta and beef mixture, covering it completely. This melty layer is important for adding richness and binding the casserole together as it bakes. Feel free to mix it up with mozzarella or another cheese of your choice if you prefer something different.

Step 8: Bake to Perfection
Place the assembled casserole in the preheated oven and bake for 10 minutes. Watch closely as the cheese melts and turns a lovely golden color. This visual cue tells you that your Homemade Ground Beef Casserole is nearing completion, ready to be the comforting meal you’ve been waiting for.

Step 9: Cool and Serve
Once baked, remove the casserole from the oven and let it cool slightly for about 5 minutes. This resting time helps the flavors to settle and makes serving easier, allowing you to portion out delicious servings of your Homemade Ground Beef Casserole without the risk of it falling apart.

Homemade Ground Beef Casserole Variations

Feel free to put your unique spin on this dish—it’s meant to be enjoyed in all its delicious forms!

Turkey Swap: Use ground turkey or chicken instead of beef for a leaner, lighter casserole. It’s just as flavorful and reduces your fat intake.
Cheese Blend: Mix different types of cheese, like gouda or pepper jack, for added complexity in flavor. The melty goodness will elevate each bite to new heights!
Pasta Variety: Swap out the penne for whole wheat or gluten-free pasta to cater to any dietary needs while still keeping that heartiness intact.
Extra Veggies: Add in diced bell peppers, spinach, or even mushrooms for a nutritious boost. This not only amps up the vitamins but also adds interesting textures throughout the casserole.
Spicy Kick: Toss in some red pepper flakes or diced jalapeños for extra heat. This twist will impress those who enjoy a bit of spice in their comfort food!
Creamy Twist: Stir in a dollop of sour cream or cream cheese before baking for a creamy texture that takes this dish to the next level of indulgence.
Freezable Meal: Make a double batch and freeze half for a future busy night. It’s always a treat to have a meal waiting in the freezer when time is short.
Italian Sausage: For a flavorful twist, replace some of the beef with Italian sausage. The seasonings in the sausage will bring an exciting depth to every forkful.

For more comforting meals that pack in flavor and warmth, check out my delicious recipes for Chinese Beef Broccoli or a quick Ground Turkey Teriyaki Stir Fry. Each option promises a delightful dining experience!

Expert Tips for Homemade Ground Beef Casserole

Perfect Pasta: Avoid overcooking the penne; it should be al dente to absorb sauce without becoming mushy during baking.
Fat Management: Drain excess fat after browning the beef. Too much grease can lead to a slippery casserole, so keep it light and flavorful.
Moisture Check: If the mixture seems dry before baking, add a splash of marinara sauce. This will ensure your Homemade Ground Beef Casserole stays juicy.
Cheese Control: If the cheese is browning too quickly, tent it with foil during the last few minutes of baking for perfect gooeyness.
Flavor Boost: Experiment with different cheeses, like mozzarella or a blend, to create a unique taste experience with each meal.
Easy Cleanup: Line your baking dish with parchment paper for easy removal and cleaning, making it a breeze to serve your casserole.

What to Serve with Homemade Ground Beef Casserole

The comforting aroma of this casserole invites the perfect companions to complete your family dinner.

Garlic Bread: The warm, buttery crunch of garlic bread is a heavenly match, perfect for soaking up any extra sauce.
Caesar Salad: Crisp romaine and tangy dressing offer a refreshing contrast to the rich, hearty casserole, elevating the meal.
Roasted Vegetables: Seasonal veggies, roasted until tender, add a touch of freshness while providing a delightful texture balance.
Steamed Green Beans: Tender green beans deliver a crisp bite and a pop of color that complements the casserole beautifully.
Homemade Coleslaw: The cool, creamy crunch of coleslaw brings a refreshing palette cleanser, making every bite of casserole feel light.
Red Wine: A glass of bold red wine enhances the deep flavors in the casserole, turning dinner into an elegant evening affair.
Brownie Sundae: Finish off the meal with a warm brownie topped with vanilla ice cream for a sweet, indulgent contrast to the savory dish.

Storage Tips for Homemade Ground Beef Casserole

Fridge: Store leftovers in an airtight container for up to 4 days. Make sure to cool the casserole down first to maintain freshness and flavor.
Freezer: You can freeze the casserole before baking or after, portions can last up to 3 months. Just ensure it’s tightly wrapped to prevent freezer burn.
Reheating: To reheat, thaw in the fridge overnight if frozen, then warm in the oven at 350°F until heated through, about 20-25 minutes. For a quick option, microwave until hot.
Serving Tips: Enjoy your Homemade Ground Beef Casserole straight from the freezer or fridge, paired with a fresh salad or garlic bread for a delicious, comforting meal.

Make Ahead Options

These Easy Homemade Ground Beef Casseroles are a fantastic meal prep option, saving you precious time on busy weeknights! You can prepare the entire casserole up to 24 hours in advance by assembling it and then covering it tightly with plastic wrap in the fridge. To maintain the quality, avoid adding the cheese until just before baking, preventing sogginess. When you’re ready to enjoy, simply preheat your oven to 400°F (200°C) and bake the casserole for about 15-20 minutes until heated through and the cheese is melted and bubbly. This way, your comforting dish will be just as delicious as if you made it fresh that day!

Homemade Ground Beef Casserole Recipe FAQs

Which pasta works best for this casserole?
Absolutely! Penne pasta is ideal because its tube shape holds onto the sauce beautifully. However, you can also use other pastas like rigatoni or even rotini. Just remember to cook it al dente, so it doesn’t become mushy when baked.

How long can I store leftovers?
You can safely refrigerate leftovers in an airtight container for up to 4 days. Make sure the casserole has cooled to room temperature before sealing it up to keep it fresh and delicious.

Can I freeze the casserole?
Yes, you can freeze your Homemade Ground Beef Casserole either before or after baking! If freezing before baking, cover it tightly with plastic wrap or foil and store it for up to 3 months. If you’ve already baked it, portion it out and freeze in airtight containers for easy individual servings.

What if my casserole is too dry?
If your casserole appears dry before baking, don’t hesitate to add a splash of marinara sauce for moisture. Simply pour a little in and gently mix it until all the pasta is coated, ensuring every bite is juicy and flavorful.

Are there any dietary considerations?
Definitely! If you have family members with dietary restrictions, consider substituting ground turkey or chicken for a lower-fat option. For gluten-free diets, you can use gluten-free pasta; just ensure all other ingredients, such as sauces and seasonings, are also gluten-free.

What if my cheese browns too fast?
Very often, if your cheese is browning too quickly, you can remedy this by tenting it with aluminum foil during the last few minutes of baking. This will prevent over-browning while still allowing the cheese to melt beautifully without becoming overly crisp.